{"product_id":"hyalaze-inj-hyaluronidase","title":"Hyalase Inj. (Hyaluronidase)","description":"\u003cp\u003e\u003cstrong\u003eHyalase Inj. (Hyaluronidase)\u003c\/strong\u003e is a sterile, freeze-dried hyaluronidase powder for injection. Each ampoule holds 1,500 international units (IU), and each box holds 10 ampoules. Hyaluronidase is an enzyme that breaks down hyaluronic acid. In aesthetic clinics it is kept on hand to dissolve hyaluronic acid fillers.\u003c\/p\u003e\n\u003cp\u003eEvery clinic that injects HA filler should stock a hyaluronidase. \u003ca href=\"\/pages\/contact-us\"\u003eContact us for trade pricing\u003c\/a\u003e.\u003c\/p\u003e\n\n\u003ch2\u003eWhat is Hyalase made of?\u003c\/h2\u003e\n\u003cp\u003eEach ampoule contains 1,500 IU of hyaluronidase as a white freeze-dried powder. There is no liquid in the ampoule. You dissolve the powder just before use.\u003c\/p\u003e\n\n\u003ch2\u003eHow does hyaluronidase work?\u003c\/h2\u003e\n\u003cp\u003eHyaluronidase splits the long hyaluronic acid chains into small fragments that the body clears. This also makes tissue more permeable for a short time, so injected fluids spread and absorb more easily. The effect on tissue is temporary.\u003c\/p\u003e\n\n\u003ch2\u003eWhat is Hyalase used for?\u003c\/h2\u003e\n\u003cp\u003eIts labelled uses are to help injected fluids, local anaesthetics and subcutaneous infusions spread, and to help the body reabsorb excess fluid or blood in tissue. In aesthetic practice, clinicians also use hyaluronidase to dissolve HA filler that is misplaced, overfilled or lumpy, and in the emergency management of filler-related vascular occlusion. The clinician decides the use and dose.\u003c\/p\u003e\n\n\u003ch2\u003eHow do you reconstitute a 1,500 IU ampoule?\u003c\/h2\u003e\n\u003cp\u003eDissolve the powder in about 1 mL of water for injections, or directly in the solution it will be combined with, immediately before use. Many clinicians then dilute further with 0.9% saline to get a workable strength. The volume sets the units per 0.1 mL:\u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eTotal volume\u003c\/th\u003e\n\u003cth\u003eIU per 1 mL\u003c\/th\u003e\n\u003cth\u003eIU per 0.1 mL\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e1 mL\u003c\/td\u003e\n\u003ctd\u003e1,500\u003c\/td\u003e\n\u003ctd\u003e150\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e3 mL\u003c\/td\u003e\n\u003ctd\u003e500\u003c\/td\u003e\n\u003ctd\u003e50\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e5 mL\u003c\/td\u003e\n\u003ctd\u003e300\u003c\/td\u003e\n\u003ctd\u003e30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e10 mL\u003c\/td\u003e\n\u003ctd\u003e150\u003c\/td\u003e\n\u003ctd\u003e15\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eThese figures are simple arithmetic, not dose advice. Use the solution straight away and discard what is left.\u003c\/p\u003e\n\n\u003ch2\u003eHyalase vs Liporase — what is the difference?\u003c\/h2\u003e\n\u003cp\u003eBoth are 1,500 IU hyaluronidase powders sold in boxes of 10. Hyalase comes in ampoules. \u003ca href=\"\/products\/liporase-inj\"\u003eLiporase\u003c\/a\u003e comes in vials and is made by Daehan New Pharm in South Korea. Choose by the brand and storage conditions your clinic prefers.\u003c\/p\u003e\n\n\u003ch2\u003eHow should Hyalase be stored?\u003c\/h2\u003e\n\u003cp\u003eDo not store above 25 °C. Keep the ampoules dry and away from light. Once reconstituted, use immediately. Check the expiry date printed on the box.\u003c\/p\u003e\n\n\u003ch2\u003eBuying Hyalase from Korean Aesthetic\u003c\/h2\u003e\n\u003cp\u003eWe ship worldwide from Seoul to licensed practitioners, clinics and distributors. Payment is arranged with our team after you order. See our \u003ca href=\"\/pages\/shipping-policy\"\u003eshipping terms\u003c\/a\u003e. Clinics usually order it alongside \u003ca href=\"\/collections\/dermal-fillers\"\u003ehyaluronic acid dermal fillers\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFor administration by trained, licensed medical professionals only.\u003c\/strong\u003e\u003c\/p\u003e\n\n\u003ch2\u003eHyalase FAQ\u003c\/h2\u003e\n\u003ch3\u003eHow many units are in one ampoule?\u003c\/h3\u003e\n\u003cp\u003e1,500 IU of hyaluronidase.\u003c\/p\u003e\n\u003ch3\u003eHow many ampoules are in a box?\u003c\/h3\u003e\n\u003cp\u003eTen.\u003c\/p\u003e\n\u003ch3\u003eDoes hyaluronidase dissolve every filler?\u003c\/h3\u003e\n\u003cp\u003eNo. It only breaks down hyaluronic acid. It does not dissolve PCL, PLLA or calcium-based products.\u003c\/p\u003e\n\u003ch3\u003eIs a skin test needed?\u003c\/h3\u003e\n\u003cp\u003eAllergic reactions to hyaluronidase can occur. Many clinicians do a patch test before non-urgent use; the clinician decides.\u003c\/p\u003e\n\u003ch3\u003eCan it be given into a vein?\u003c\/h3\u003e\n\u003cp\u003eNo. Hyalase is not for intravenous use.\u003c\/p\u003e\n","brand":"upkeepskin","offers":[{"title":"Default Title","offer_id":46883673309466,"sku":null,"price":290.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/5053\/3658\/files\/HyalazeInj._Hyaluronidase.jpg?v=1695967539","url":"https:\/\/koreanaesthetic.com\/products\/hyalaze-inj-hyaluronidase","provider":"Korean Aesthetic","version":"1.0","type":"link"}