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Hyalase® 1500 I.U. – Hyaluronidase Powder for Injection
Product Description
Hyalase® 1500 I.U. is a sterile, freeze-dried powder containing hyaluronidase, an enzyme that temporarily depolymerizes hyaluronic acid in the extracellular matrix. This action enhances the permeability of connective tissues, facilitating the dispersion and absorption of co-administered injectables. It is commonly utilized in aesthetic medicine to dissolve hyaluronic acid-based dermal fillers and to improve the efficacy of subcutaneous or intramuscular injections.
Formulation
Each ampoule contains:
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Active Ingredient: Hyaluronidase 1500 International Units (I.U.)
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Form: White, sterile, freeze-dried powder for solution
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Solvent: To be reconstituted with approximately 1 ml of water for injections or directly in the solution with which Hyalase® is to be combined .
Indications
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Enhancement of dispersion and absorption of subcutaneous or intramuscular injections
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Adjunct to local anesthetics to improve efficacy
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Promotion of resorption of excess fluids and blood in tissues
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Dissolution of hyaluronic acid-based dermal fillers in aesthetic treatments
Benefits
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Rapid action in breaking down hyaluronic acid, aiding in the correction of overfilling or misplacement of dermal fillers
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Facilitates improved distribution of co-injected medications, enhancing their therapeutic effects
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Supports faster recovery from complications such as hematomas or edema by promoting fluid resorption
Scope of Application
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Aesthetic medicine: Management of complications from dermal fillers, such as vascular occlusion or nodules
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Medical treatments: Enhancing the effectiveness of subcutaneous infusions and local anesthetics
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Emergency use: Treatment of extravasation injuries by dispersing infiltrated substances
Duration of Effect
The enzymatic activity of hyaluronidase is immediate upon administration, with effects lasting for a limited period. The duration depends on the amount administered and the specific clinical scenario. Repeat dosing may be necessary based on the patient's response and the extent of hyaluronic acid presence .
Packaging and Specifications
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Packaging: Box containing 10 ampoules
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Dosage Form: Each ampoule contains 1500 I.U. of hyaluronidase powder
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Storage: Store below 25°C in a dry place, protected from light. Reconstituted solutions should be used immediately .