Lidocaine HCI 2%

Lidocaine HCl 2% Injection is a fast-acting, intermediate-duration local anesthetic used in medical and dental procedures requiring nerve block or infiltration. Its 20 mg/mL concentration ensures effective pain control with a rapid onset of action. Safe, reliable, and widely used, this sterile solution supports both minor and major interventions in clinical settings.

Formulation

• Active Ingredient: Lidocaine Hydrochloride 20 mg/mL – an amide-type local anesthetic that blocks sodium channels in nerve membranes, preventing nerve impulse transmission and resulting in localized numbness.

• Excipients: Sodium Chloride 6 mg/mL, Water for Injection

• pH Adjustment: Sodium hydroxide and/or hydrochloric acid to maintain pH 5.0–7.0

• Preservative: May include methylparaben (in multi-dose formulations)

• Form: Sterile aqueous solution for parenteral administration

Benefits

• Rapid onset of anesthesia (2–5 minutes)

• Intermediate duration of action (1–2 hours)

• Applicable to a wide range of anesthetic techniques

• Effective for local, regional, and dental anesthesia

• Proven safety with consistent clinical outcomes

Scope of Application

• Local infiltration anesthesia

• Peripheral nerve blocks (e.g., brachial plexus, intercostal)

• Central neural blocks (e.g., epidural, caudal)

• Dental and oral surgical procedures

• Minor outpatient and emergency interventions

Indication

• Induction of local or regional anesthesia via infiltration or nerve block

• Emergency management of ventricular arrhythmias (IV route)

• Anesthetic adjunct for surgical and diagnostic procedures

Duration of Effect

• Onset: 2–5 minutes after injection

• Effect Duration: Typically 60–120 minutes, depending on dosage and site

• Metabolism: Liver metabolism with renal excretion; caution advised in hepatic impairment

Packaging and Specifications

• Concentration: 2% (20 mg/mL)

• Available Volumes: 5 mL, 10 mL, 20 mL, and 50 mL vials

• Form: Single-dose and multi-dose vials

• Storage: Keep at 15°C–30°C, away from direct light

• Shelf Life: As indicated on product packaging